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Frequently Asked Questions about aiPyx

Welcome to aiPyx’s FAQ page. Here, you will find answers to the most commonly asked questions about our pioneering biotechnology company and the services and products we provide. Our patented dosage approach for accurately assessing calcification in the human body, with a primary focus on nephrology, rheumatology, and cardiology, provides a unique tool for addressing key pathologies and rare diseases. We will be answering questions such as: what are the signs that lead to a diagnosis of PXE? How rare is PXE? and what are the effects of PXE? If you don’t find the answer you are looking for, please reach out to us anytime by phone, chat, or email.

Question: What are the signs that lead to the diagnosis of PXE?


PXE (Pseudoxanthoma Elasticum) often presents with skin changes as the initial sign, which can vary among individuals. These skin changes include small yellowish bumps or lesions on the neck, armpits, or other flexural areas. Additionally, visible signs of PXE can occur in the eyes, such as angioid streaks, which are breaks in the Bruch’s membrane of the retina.

It’s important to note that the diagnosis of PXE is made based on a combination of clinical findings, family history, and genetic testing. A physician or dermatologist experienced in diagnosing PXE can assess the overall pattern of signs and symptoms to determine if further testing is necessary.

Question: How rare is PXE?


PXE (Pseudoxanthoma Elasticum) is considered a rare disorder, with estimated incidence rates varying among different populations and studies. While precise figures are difficult to determine, it is generally believed to affect approximately 1 in 25,000 to 100,000 individuals worldwide. It is important to note that some cases of PXE may go undiagnosed or misdiagnosed, contributing to the challenge of accurately assessing its prevalence.

Question: What are the effects of PXE?


The effects of PXE (Pseudoxanthoma Elasticum) can vary and affect different parts of the body. This condition primarily affects the elastic tissue in various organs and systems, leading to a range of symptoms.

In the skin, PXE can cause small yellowish bumps or lesions, particularly in flexural areas like the neck, armpits, and groin. These skin changes are often one of the initial signs of the condition.

PXE can also impact the eyes, with the appearance of angioid streaks. These streaks are breaks in the Bruch’s membrane of the retina, which can lead to vision problems.

The cardiovascular system can be affected as well, with the potential for arterial calcifications and increased risks of cardiovascular diseases. This may include conditions like high blood pressure, heart disease, and stroke.

In some cases, PXE can also have gastrointestinal implications, such as digestive problems or gastrointestinal bleeding.

It’s important to note that the effects of PXE can vary among individuals, and there is no predictable pattern or progression of symptoms. Therefore, it is crucial for individuals with PXE to receive proper medical evaluation and ongoing management in order to address their specific symptoms and needs.

Discover how aiPyx can help reliably measure body calcification. Get in touch with us today and experience the benefits of our leading technology and patented dosage approach.